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Researcher Profile - Eric Agdeppa Get Newsletter
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Home: Community: Researcher Profiles
Researcher Profile

RESEARCHER INFORMATION
First Name:Eric
Last Name:Agdeppa
Title:Research Scientist
Advanced Degrees:Ph.D.
Affiliation:General Electric Global Research
Department:Laboratory of Molecular Biology & Biochemstry / Biotechnology - Advanced Technology Program
Street Address 1:One Research Circle
Street Address 2:Bldg. K1, Rm. 3C27
City:Niskayuna
State/Province:NY
Zip/Postal Code:12309
Country/Territory:U.S.A.
Disclosure:
(view policy) 
Member reports the following financial or other potential conflicts of interest: [Last Modified: 29 December 2003]

I am currently an employee of General Electric.
Clinical Interests:
Alzheimer Disease, Tauopathies, Prion Diseases
Research Focus:
Animal Models, PET molecular imaging, Brain imaging, Chemistry/Pharmacology, Protein structure/chemistry, Drug screening, Microscopy, Bioinformatics/Statistics, Neuropathology, Diagnosis, Proteomics, Tau/Cytoskeleton, A-beta PP/A-beta
Work Sector(s):
Industry
Web Sites:
Professional: http://www.crd.ge.com/
Lab: http://www.crd.ge.com/cooltechnologies/advtechnology_biotechnology.jsp
Researcher Bio
Currently, I am a research scientist in the Biotechnology - Advanced Technology Program at the General Electric Global Research Center. Our Biotechnology program has expertise in biomarker discovery, molecular imaging, heterogeneous data integration and computer aided prognostics.
GE Global Research will have a major influence on how GE influences medicine and how it is delivered in the future.
Top Papers
1: Agdeppa ED, Kepe V, Petri A, Satyamurthy N, Liu J, Huang SC, Small GW, Cole GM, Barrio JR. In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile. Neuroscience. 2003;117(3):723-30.
PMID: 12617976 [PubMed - indexed for MEDLINE]

2: Agdeppa ED, Kepe V, Liu J, Small GW, Huang SC, Petric A, Satyamurthy N, Barrio JR. 2-dialkylamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs): novel diagnostic and therapeutic tools in Alzheimer's disease. Mol Imaging Biol. 2003 Nov;5(6):404-17.
PMID: 14667495 [PubMed - in process]

3: Small GW, Agdeppa ED, Kepe V, Satyamurthy N, Huang SC, Barrio JR. In vivo brain imaging of tangle burden in humans. J Mol Neurosci. 2002 Dec;19(3):323-7. Review.
PMID: 12540059 [PubMed - indexed for MEDLINE]

4: Shoghi-Jadid K, Small GW, Agdeppa ED, Kepe V, Ercoli LM, Siddarth P, Read S, Satyamurthy N, Petric A, Huang SC, Barrio JR. Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease. Am J Geriatr Psychiatry. 2002 Jan-Feb;10(1):24-35.
PMID: 11790632 [PubMed - indexed for MEDLINE]

5: Agdeppa ED, Kepe V, Liu J, Flores-Torres S, Satyamurthy N, Petric A, Cole GM, Small GW, Huang SC, Barrio JR. Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J Neurosci. 2001 Dec 15;21(24):RC189.
PMID: 11734604 [PubMed - indexed for MEDLINE]

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